Accounting Policies [Abstract] Accounting Policies [Abstract] Accounts Payable, Current Accounts payable Accrued Liabilities, Current Accrued expenses Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Less: accumulated depreciation Additional Paid in Capital, Common Stock Additional paid-in capital Adjustment of Warrants Granted for Services Warrant expense Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Allocated Share-based Compensation Expense Stock-based compensation expense Amendment Flag Amendment Flag Amortization of Financing Costs Amortization of deferred financing costs Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Anti-dilutive securities excluded from computation of earnings per share Antidilutive Securities [Axis] Antidilutive Securities [Axis] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Arrangements and Non-arrangement Transactions [Domain] Arrangements and Non-arrangement Transactions [Domain] Assets Total assets Assets, Current Total current assets Assets, Current [Abstract] Current assets: Assets, Fair Value Disclosure, Recurring Assets, fair value disclosure, recurring Award Type [Axis] Award Type [Axis] Cash and Cash Equivalents [Abstract] Cash and Cash Equivalents [Abstract] Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents-End of period Cash and cash equivalents-Beginning of period Cash and cash equivalents Cash and Cash Equivalents [Axis] Cash and Cash Equivalents [Axis] Cash and Cash Equivalents, Fair Value Disclosure Cash and cash equivalents, fair value Cash and Cash Equivalents [Line Items] Cash and Cash Equivalents [Line Items] Cash and Cash Equivalents, Period Increase (Decrease) Net decrease in cash and cash equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Cash and Cash Equivalents Class of Stock [Domain] Class of Stock [Domain] Class of Warrant or Right [Axis] Class of Warrant or Right [Axis] Class of Warrant or Right [Domain] Class of Warrant or Right [Domain] Class of warrant or right exercisable expiration period. Class Of Warrant Or Right Exercisable Expiration Period Warrants expiry period Class of warrant or right exercisable period. Class Of Warrant Or Right Exercisable Period Warrants exercisable period Class of Warrant or Right, Exercise Price of Warrants or Rights Class of Warrants or right to purchase common stock, exercise price Class of Warrant or Right [Line Items] Class of Warrant or Right [Line Items] Class of Warrant or Right, Number of Securities Called by Warrants or Rights Class of Warrants or right to purchase common stock Net exercise of warrants, shares Class of warrant or right number of securities surrendered. Class Of Warrant Or Right Number Of Securities Surrendered Surrender of warrant to satisfy other liability Class of Warrant or Right [Table] Class of Warrant or Right [Table] Collagen Supply Agreement [Member] Collagen Supply Agreement [Member] Collagen Supply Agreement [Member] Commitments and Contingencies Commitments and contingencies (Note 5) Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Text Block] Commitments and Contingencies Common Stock, Par or Stated Value Per Share Common stock, par value Common Stock, Shares Authorized Common stock, shares authorized Common Stock, Shares, Issued Common stock, shares issued Common Stock, Shares, Outstanding Common stock, shares outstanding Common Stock, Value, Issued Common stock, $0.01 par value; authorized shares-100,000,000 at September 30, 2015 and December 31, 2014; 13,273,470 shares issued and outstanding at September 30, 2015 and 12,755,012 shares issued and outstanding at December 31, 2014 Compensation Related Costs [Abstract] Compensation Related Costs [Abstract] Compensation Related Costs, Policy [Policy Text Block] Stock-Based Compensation Construction in Progress [Member] Construction in Progress [Member] Consulting Agreement Warrant Member Consulting Agreement Warrant Member Consulting Agreement Warrant [Member] Contractual Obligation One-time payment amount Contractual Obligation, Future Minimum Payments Due, Remainder of Fiscal Year Potential milestone payment Conversion of Stock, Shares Converted Conversion of redeemable preferred stock and accrued dividends Current Fiscal Year End Date Current Fiscal Year End Date Debt Conversion, Converted Instrument, Amount Convertible notes payable to common stock Debt Conversion, Converted Instrument, Shares Issued Accrued interest to common stock Debt Instrument, Basis Spread on Variable Rate Line of credit facility, basis spread on variable rate Debt Instrument, Interest Rate, Stated Percentage Line of credit facility, interest rate, stated percentage Debt Instrument, Term Bank loan and security agreement, repayment period Deferred rent and lease incentive. Deferred Rent And Lease Incentive Deferred rent and lease incentive Deferred Rent Credit, Current Current portion of deferred rent Deferred Rent Credit, Noncurrent Deferred rent, long-term Deferred Tax Assets, Net of Valuation Allowance, Noncurrent Noncurrent deferred tax assets, net Deferred Tax Liabilities, Net, Current Current deferred tax liability, net Deferred tax liabilities, net Demand Deposits [Member] Cash Deposits [Member] Depreciation Depreciation Depreciation expense Disclosure of Compensation Related Costs, Share-based Payments [Abstract] Disclosure of Compensation Related Costs, Share-based Payments [Abstract] Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Stock-Based Compensation Document And Entity Information [Abstract] Document And Entity Information [Abstract] Document And Entity Information [Abstract] Document Fiscal Period Focus Document Fiscal Period Focus Document Fiscal Year Focus Document Fiscal Year Focus Document Period End Date Document Period End Date Document Type Document Type Earnings Per Share [Abstract] Earnings Per Share [Abstract] Earnings Per Share, Basic and Diluted Loss per common share-basic and diluted: Earnings Per Share [Text Block] Loss Per Common Share Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition Unrecognized compensation cost, recognition period Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Share-based Awards Other than Options Unrecognized compensation cost related to restricted stock awards Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options Unrecognized compensation cost related to outstanding options Employee Stock Option [Member] Stock Options [Member] Engineering Agreement [Member] Engineering Agreement [Member] Engineering Agreement [Member] Entity Central Index Key Entity Central Index Key Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Entity [Domain] Entity [Domain] Entity Filer Category Entity Filer Category Entity Registrant Name Entity Registrant Name Equipment [Member] Laboratory Equipment [Member] Equity Component [Domain] Equity Component [Domain] Fair Value, Assets Measured on Recurring Basis [Table Text Block] Summary of Cash Equivalents Measured at Fair Value on Recurring Basis Fair Value Assumptions, Expected Term Fair value of the warrants, expected term to liquidity Fair Value Assumptions, Expected Volatility Rate Fair value of the warrants, implied volatility Fair Value Assumptions, Risk Free Interest Rate Fair value of the warrants, risk free interest rate Fair Value, Hierarchy [Axis] Fair Value, Hierarchy [Axis] Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Fair Value, Inputs, Level 1 [Member] Prices in Active Markets (Level 1) [Member] Fair Value, Inputs, Level 2 [Member] Significant Other Observable Inputs (Level 2) [Member] Fair Value, Inputs, Level 3 [Member] Significant Unobservable Inputs (Level 3) [Member] Fair Value Measurement, Policy [Policy Text Block] Fair Value Measurements Fair Value Hierarchy [Domain] Fair Value Hierarchy [Domain] Finite-Lived Intangible Assets, Accumulated Amortization Accumulated Impairment Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets, Gross Cost Finite-Lived Intangible Assets [Line Items] Finite-Lived Intangible Assets [Line Items] Finite-Lived Intangible Assets, Major Class Name [Domain] Finite-Lived Intangible Assets, Major Class Name [Domain] Finite-Lived Intangible Assets, Net Intangible asset, net Net Book Value General and Administrative Expense General and administrative General and Administrative Expense [Member] General and Administrative [Member] Goodwill and Intangible Assets Disclosure [Abstract] Goodwill and Intangible Assets Disclosure [Abstract] Goodwill and Intangible Assets, Policy [Policy Text Block] Intangible Assets Grants Receivable Accrued and received grants, aggregate Hydrogel License Agreement [Member] Hydrogel License Agreement [Member] Hydrogel License Agreement [Member] ISRAEL Israel [Member] Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill) Impairment of intangible assets Incentive from Lessor Deferred lease incentive, long-term Income Statement [Abstract] Income Statement [Abstract] Income Statement Location [Axis] Income Statement Location [Axis] Income Statement Location [Domain] Income Statement Location [Domain] Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Income Tax Disclosure [Text Block] Income Taxes Increase (Decrease) in Accounts Payable Accounts payable Increase (Decrease) in Accrued Liabilities Accrued expenses Increase (Decrease) in Other Noncurrent Assets Other non-current assets Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other current assets Indefinite-lived Intangible Assets [Axis] Indefinite-lived Intangible Assets [Axis] Indefinite-lived Intangible Assets, Major Class Name [Domain] Indefinite-lived Intangible Assets, Major Class Name [Domain] In Process Research and Development [Member] IPR&D [Member] Interest Expense Interest expense, net IPO [Member] IPO [Member] Leasehold Improvements [Member] Leasehold Improvements [Member] Lease Incentive, Payable, Current Current portion of deferred lease incentive Legal Entity [Axis] Legal Entity [Axis] Lexington [Member] Lexington [Member] Lexington [Member] Liabilities Total liabilities Liabilities and Equity Total liabilities and stockholders' equity Liabilities, Current Total current liabilities Liabilities, Current [Abstract] Current liabilities: Liabilities, Fair Value Adjustment Change in fair value of warrant liability, other liability and net sales distribution payment liability Change in fair value of liabilities Financial and Nonfinancial Liabilities, Fair Value Disclosure Liabilities, fair value disclosure Liabilities, Fair Value Disclosure, Recurring Liabilities, fair value disclosure, recurring Line of Credit Facility, Maximum Borrowing Capacity Aggregate maximum amount of line of credit facility Loans Payable, Current Current portion of equipment loan Loans Payable, Noncurrent Equipment loan, long-term Long-term Purchase Commitment, Amount Minimum amount of material and/or services Category of Item Purchased [Axis] Category of Item Purchased [Axis] Long-term Purchase Commitment, Category of Item Purchased [Domain] Long-term Purchase Commitment, Category of Item Purchased [Domain] Long-term Purchase Commitment, Description Supplier agreement description Long-term Purchase Commitment, Period Initial term of the agreement Loss Contingency Nature [Axis] Loss Contingency Nature [Axis] Loss Contingencies [Line Items] Loss Contingencies [Line Items] Loss Contingencies [Table] Loss Contingencies [Table] Loss Contingency, Nature [Domain] Loss Contingency, Nature [Domain] MASSACHUSETTS Massachusetts [Member] Maximum [Member] Maximum [Member] Minimum [Member] Minimum [Member] Money Market Funds [Member] Money Market Funds [Member] Nature Of Business [Abstract] Nature Of Business [Abstract] Nature Of Business [Abstract] Nature Of Business And Basis Of Presentation [Line Items] Nature Of Business And Basis Of Presentation [Line Items] Nature Of Business And Basis Of Presentation [Line Items] Nature Of Business And Basis Of Presentation [Table] Nature Of Business And Basis Of Presentation [Table] Nature Of Business And Basis Of Presentation [Table] Nature of Operations [Text Block] Nature of Business Net Cash Provided by (Used in) Financing Activities, Continuing Operations Net cash provided by financing activities Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] CASH FLOWS FROM FINANCING ACTIVITIES Net Cash Provided by (Used in) Investing Activities, Continuing Operations Net cash used in investing activities Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] CASH FLOWS FROM INVESTING ACTIVITIES: Net Cash Provided by (Used in) Operating Activities, Continuing Operations Net cash used in operating activities Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] CASH FLOWS FROM OPERATING ACTIVITIES: Net Income (Loss) Attributable to Parent Net loss Net loss Net Income Loss Available To Common Stockholders Basic And Diluted Net Income Loss Available To Common Stockholders Basic And Diluted Loss attributable to common stockholders-basic and diluted New Accounting Pronouncements, Policy [Policy Text Block] Recent Accounting Pronouncements Non cash consideration for licensed technology. Non Cash Consideration For Licensed Technology Non-cash consideration for licensed technology Long-Lived Assets Long-lived assets Nonoperating Income (Expense) Total other income (expense), net Non refundable license fee payable. Non Refundable License Fee Payable Non-refundable license fee Nonvested Restricted Stock Shares Activity [Table Text Block] Schedule of Restricted Stock Awards Under the 2012 and 2013 Plans Ocs Agreement [Member] Ocs Agreement [Member] OCS Agreement [Member] Office Equipment [Member] Office Equipment [Member] Operating Expenses Total operating expenses Operating Expenses [Abstract] Operating expenses: Operating Income (Loss) Loss from operations Operating lease expiration period. Operating Lease Expiration Period Lease expiration period Operating Leases, Rent Expense, Net Rent expense under operating lease agreements Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] Other Income and Expenses [Abstract] Other income (expense): Other Liability [Member] Other Liability [Member] Other Liability [Member] Other Nonoperating Income (Expense) Other income (expense), net Over-Allotment Option [Member] Over-Allotment Option [Member] Payment For License Agreement Reimbursement Of Costs Payment For License Agreement Reimbursement Of Costs Reimbursement for development cost Payments for (Proceeds from) Tenant Allowance Construction allowance to total cost of tenant improvements Payments for Repurchase of Initial Public Offering Costs associated with Initial Public Offering Payments of Stock Issuance Costs Issuance costs Payments to Acquire Property, Plant, and Equipment Purchases of property and equipment Payments to Suppliers Amount paid to suppliers Percentage of royalty offsetting. Percentage Of Royalty Offsetting Percentage of royalty offsetting Plasmid License Agreement [Member] Plasmid License Agreement [Member] Plasmid License Agreement [Member] Preferred Stock, Par or Stated Value Per Share Preferred stock par value Preferred Stock, Shares Authorized Preferred stock authorized Preferred stock shares authorized Preferred Stock, Shares Issued Preferred stock issued Preferred Stock, Shares Outstanding Preferred stock outstanding Preferred Stock, Value, Issued Preferred stock, $0.01 par value; authorized shares-10,000,000 at September 30, 2015 and December 31, 2014; none issued and outstanding at September 30, 2015 and December 31, 2014 Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Reclassification, Policy [Policy Text Block] Reclassifications Proceeds from Issuance Initial Public Offering Gross proceeds from initial public offering Proceeds from issuance initial public offering net. Proceeds From Issuance Initial Public Offering Net Net proceeds from initial public offering Proceeds from Issuance of Common Stock Proceeds from overallotment, net of issuance costs Proceeds from Issuance of Debt Borrowings under equipment term loan Proceeds from Issuance of Preferred Stock and Preference Stock Issuance of Series A-1 preferred stock, net of cash issuance costs of $73 Proceeds from Stock Options Exercised Proceeds from the exercise of common stock options Property, Plant and Equipment [Abstract] Property, Plant and Equipment [Abstract] Property, Plant and Equipment, Type [Axis] Property, Plant and Equipment, Type [Axis] Property, Plant and Equipment Disclosure [Text Block] Property and Equipment Property, Plant and Equipment, Gross Total property and equipment Property, Plant and Equipment [Line Items] Property, Plant and Equipment [Line Items] Property, Plant and Equipment, Net Property and equipment, net Property and equipment, net Property, Plant and Equipment [Table Text Block] Schedule of Property and Equipment Property, Plant and Equipment, Type [Domain] Property, Plant and Equipment, Type [Domain] Purchase commitment non-refundable payment. Purchase Commitment Nonrefundable Payment Non-refundable payment Purchase Commitment, Remaining Minimum Amount Committed Purchase amount, remaining to be paid Range [Axis] Range [Axis] Range [Domain] Range [Domain] Name of Property [Axis] Name of Property [Axis] Name of Property [Domain] Name of Property [Domain] Redeemable Convertible Preferred Stock [Member] Convertible Redeemable Preferred Stock and Dividends [Member] Repayments of Debt Payment on equipment term loan Research and Development Arrangement, Contract to Perform for Others, Type [Axis] Research and Development Arrangement, Contract to Perform for Others, Type [Axis] Research and Development Arrangement, Contract to Perform for Others, Type [Domain] Research and Development Arrangement, Contract to Perform for Others, Type [Domain] Research and Development Expense Research and development Research and development expense Research and Development Expense [Member] Research and Development [Member] Cash and Cash Equivalents [Domain] Cash and Cash Equivalents [Domain] Restricted Cash and Cash Equivalents, Noncurrent Restricted cash Restricted Stock [Member] Restricted Stock [Member] Retained Earnings (Accumulated Deficit) Accumulated deficit Royalty Expense Non-refundable royalty fee Royalty payment percentage. Royalty Payment Percentage Royalties payment, rate Royalty payment percentage as percentage of grant received. Royalty Payment Percentage As Percentage Of Grant Received Royalty payment percentage as percentage of grant received Sale of Stock [Domain] Sale of Stock [Domain] Sale of Stock, Price Per Share Initial public offering price per share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share Schedule of Cash and Cash Equivalents [Table] Schedule of Cash and Cash Equivalents [Table] Schedule of Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Table Text Block] Summary of Stock-Based Compensation by Award Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block] Summary of Stock-Based Compensation for All Options Granted and Restricted Stock Awards Schedule of Finite-Lived Intangible Assets [Table] Schedule of Finite-Lived Intangible Assets [Table] Schedule of Finite-Lived Intangible Assets [Table Text Block] Summary of Intangible Assets, Net of Accumulated Impairment Charges Property, Plant and Equipment [Table] Property, Plant and Equipment [Table] Schedule of Revenue from External Customers and Long-Lived Assets, by Geographical Areas [Table Text Block] Summary of Operations in Different Geographic Regions Schedule of Segment Reporting Information, by Segment [Table] Schedule of Segment Reporting Information, by Segment [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] Summary of Stock Option Activity Under the 2012 and 2013 Plans Schedule of Share-based Goods and Nonemployee Services Transaction by Supplier [Table Text Block] Summary of Weighted-Average Assumptions Used in the Black-Scholes Option Pricing Model to Determine the Fair Value of the Non-Employee Stock Option Grants Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Summary of Weighted-Average Assumptions Used in the Black-Scholes Option Pricing Model to Determine the Fair Value of the Employee Stock Option Grants Security Deposit Stand-by letter of credit maintained by company Geographical [Domain] Geographical [Domain] Segment Reporting [Abstract] Segment Reporting [Abstract] Segment Reporting Information [Line Items] Segment Reporting Information [Line Items] Segment Reporting, Policy [Policy Text Block] Segment and Geographic Information Series A Preferred Stock [Member] Series A Preferred Stock [Member] Share-based Compensation Stock-based compensation Share-based Compensation, Allocation and Classification in Financial Statements [Abstract] Share-based Compensation, Allocation and Classification in Financial Statements [Abstract] Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number Number of shares, Unvested ending balance Number of shares, Unvested beginning balance Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Weighted-average grant date fair value, Unvested ending balance Weighted-average grant date fair value, Unvested beginning balance Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period Vesting of restricted stock Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract] Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract] Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividend yield Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term Expected term (in years) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate Expected volatility Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Risk-free interest rate Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value Aggregate Intrinsic Value, Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Number of Options, Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Weighted Average Exercise Price, Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Weighted Average Remaining Contractual Term, Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period Number of Options, Cancelled Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Number of Options, Granted Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Weighted average grant date fair value per share of employee option granted Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value Aggregate Intrinsic Value, Outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Number of Options, Outstanding Ending Balance Number of Options, Outstanding Beginning Balance Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Weighted Average Exercise Price, Outstanding Ending Balance Weighted Average Exercise Price, Outstanding Beginning Balance Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Grant Date Fair Value Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Grant Date Fair Value Weighted average grant date fair value of shares outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Weighted Average Remaining Contractual Term, Outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Aggregate Intrinsic Value, Vested and expected to vest outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Number of Options, Vested and expected to vest outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Weighted Average Exercise Price, Vested and expected to vest outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Weighted Average Remaining Contractual Term, Vested and expected to vest outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Weighted Average Grant Date Fair Value Weighted average grant date fair value of vested options Equity Award [Domain] Equity Award [Domain] Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Weighted Average Exercise Price, Cancelled Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Weighted Average Exercise Price, Granted Share-based Goods and Nonemployee Services Transaction [Abstract] Share-based Goods and Nonemployee Services Transaction [Abstract] Share-based Goods and Nonemployee Services Transaction, Valuation Method, Expected Dividend Rate Expected dividend yield Share-based Goods and Nonemployee Services Transaction, Valuation Method, Expected Term Expected term (in years) Share-based Goods and Nonemployee Services Transaction, Valuation Method, Expected Volatility Rate Expected volatility Share-based Goods and Nonemployee Services Transaction, Valuation Method, Risk Free Interest Rate Risk-free interest rate Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Silicon Valley Bank [Member] Silicon Valley Bank [Member] Silicon Valley Bank [Member] Software Development [Member] Software [Member] Standby Letters of Credit [Member] Stand-By Letter of Credit [Member] Class of Stock [Axis] Class of Stock [Axis] Equity Components [Axis] Equity Components [Axis] Geographical [Axis] Geographical [Axis] Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Stock Compensation Plan [Member] Restricted Stock and Options to Purchase Common Stock [Member] Stockholders' Equity Attributable to Parent Total stockholders' equity Stockholders' Equity Attributable to Parent [Abstract] Stockholders' equity: Stock Issued During Period, Shares, New Issues Sale of common stock shares Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Exercised Sale of Stock [Axis] Sale of Stock [Axis] Summary Of Significant Accounting Policies [Line Items] Summary Of Significant Accounting Policies [Line Items] Summary Of Significant Accounting Policies [Line Items] Summary Of Significant Accounting Policies [Table] Summary Of Significant Accounting Policies [Table] Summary Of Significant Accounting Policies [Table] Text Block [Abstract] Text Block [Abstract] Tissue Processor Sub License Agreement [Member] Tissue Processor Sub License Agreement [Member] Tissue Processor Sub License Agreement [Member] Tissue Regeneration License Agreement [Member] Tissue Regeneration License Agreement [Member] Tissue Regeneration License Agreement [Member] Trading Symbol Trading Symbol Type of Arrangement and Non-arrangement Transactions [Axis] Type of Arrangement and Non-arrangement Transactions [Axis] UNITED STATES United States [Member] Waltham [Member] Waltham [Member] Waltham [Member] Warrant [Disclosure Text Block] Warrant [Disclosure Text Block] Warrants Warrant Liability [Member] Warrant Liability [Member] Warrant Liability [Member] Warrant [Member] Warrants Exercisable into Common Stock [Member] Warrants and Rights Note Disclosure [Abstract] Warrants and Rights Note Disclosure [Abstract] Warrants Not Settleable in Cash, Fair Value Disclosure Fair value of warrants Weighted Average Number of Shares Outstanding, Basic and Diluted Weighted-average shares used to compute earnings per common share-basic and diluted: Weighted Average Number of Shares Outstanding, Basic Instruments outstanding